Will my graphics card work in all PCIe slots?

Both the blue slots are PCIe x16 The difference is that the 2nd PCIe 16x is capable of wiring

You didn't provide 'what' card, some cards work in 16x slot Your 4x slots are PCIe spec bandwidth So

candy star slot No problem whatsoever Also, if you look closely, the bottom x16 slot is actually a x4 slot in the outer shape of a x16 slot See how the pins

candibet slot Here is AMD's Crossfire compatibility chart to help you understand which cards will work together in crossfire and yes x16 and x4 will work fine