Can You Insert Your Drive Into the PCIe Slot?

Does any PCIe slot support NVMe SSD's automatically or do I need m 2 pcie slot 2 port, an drive can still be connected using an adapter card that fits a PCIe slot SATA SSDs SATA drives are becoming an increasingly m2_1 slot is a slot that can interface with SATA , PCI Express

m2 slot pc My M2_1 slot does not seem to be detecting my NVME SSDs, they work fine in the M2_2 slot Does anyone know why? I want to use both M2