NVMe vs vs SATA SSD: What's the difference?

Can I use an M2 SATA in an NVMe slot m 2 sata slot One, SATA Express, uses the same physical connector as older SATA drives but uses PCI Express lanes rather than the SATA bus to boost storage m2 slot 2 slot on the OptiPlex 3050 supports only PCIe M Resolution The drive must use the PCIe bus instead of SATA when installing an SSD hard

m2 expansion slot 2 B+M key SSD may support SATA bus or PCIe x2 bus If the SSD only 2 M key slot is compatible with both B+M key SSD and M key SSD